Cellosaurus cell line NPC-KT (CVCL

Cellosaurus NPC-KT (CVCL_X204)

Cross-references
Cell line name	NPC-KT
Accession	CVCL_X204
Resource Identification Initiative	To cite this cell line use: NPC-KT (RRID:CVCL_X204)
Comments	Characteristics: Hybrid of an EBV-positive NPC cells from 74 year old Japanese female with Ad-AH cells. Doubling time: 24 hours (PubMed=6088881). Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Omics: Transcriptome analysis by RNAseq.
Disease	Nasopharyngeal carcinoma (NCIt: C3871) Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_X200 (Ad-AH)
Category	Hybrid cell line
Publications	PubMed=6088881; DOI=10.1093/jnci/73.3.711 Takimoto T., Ogura H., Ohno S., Umeda R., Hatano M. Tumorigenicity of nasopharyngeal carcinoma hybrid cell line. J. Natl. Cancer Inst. 73:711-715(1984) PubMed=6318711; DOI=10.1007/BF00454266 Takimoto T., Kamide M., Umeda R. Establishment of Epstein-Barr virus (EBV)-associated nuclear antigen (EBNA)-positive nasopharyngeal carcinoma hybrid cell line (NPC-KT). Arch. Otorhinolaryngol. 239:87-92(1984) PubMed=3008992 Takimoto T., Sato H., Ogura H., Miyawaki T., Glaser R. Superinfection of epithelial hybrid cells (D98/HR-1, NPC-KT, and A2L/AH) with Epstein-Barr virus and the relationship to the C3d receptor. Cancer Res. 46:2541-2544(1986) PubMed=24991015; DOI=10.1128/JVI.01457-14; PMCID=PMC4178894 Strong M.J., Baddoo M., Nanbo A., Xu M., Puetter A., Lin Z. Comprehensive high-throughput RNA sequencing analysis reveals contamination of multiple nasopharyngeal carcinoma cell lines with HeLa cell genomes. J. Virol. 88:10696-10704(2014)
Cell line databases/resources	TOKU-E; 4071
Encyclopedic resources	Wikidata; Q54930970
Entry history
Entry creation	17-Jul-2014
Last entry update	21-Mar-2023
Version number	8