ID   UT-EC-2B
AC   CVCL_X005
SY   University of Turku-Endometrial Carcinoma-2B
DR   IARC_TP53; 21689
DR   Wikidata; Q54992045
RX   PubMed=7798295;
RX   PubMed=7821848;
RX   PubMed=8123477;
RX   PubMed=9887230;
RX   PubMed=17178626;
CC   Doubling time: 30 hours (Note=At 14th passage) (PubMed=7821848).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=9887230).
CC   Derived from site: Metastatic; Supraclavicular lymph node; UBERON=UBERON_0035279.
DI   NCIt; C114656; Endometrial adenosquamous carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_X004 ! UT-EC-2A
OI   CVCL_WM05 ! UT-EC-2C
SX   Female
AG   45-46Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 13
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RX   PubMed=7798295; DOI=10.1007/BF01194268;
RA   Rantanen V., Grenman S.E., Kulmala J., Alanen K., Lakkala T.,
RA   Grenman R.;
RT   "Sublethal damage repair after fractionated irradiation in endometrial
RT   cancer cell lines tested with the 96-well plate clonogenic assay.";
RL   J. Cancer Res. Clin. Oncol. 120:712-716(1994).
//
RX   PubMed=7821848; DOI=10.1006/gyno.1995.1009;
RA   Rantanen V., Grenman S.E., Kulmala J., Jaakkola M., Lakkala T.,
RA   Sajantila A., Klemi P., Grenman R.;
RT   "Characterization and radiosensitivity of UT-EC-2A and UT-EC-2B, two
RT   new highly radiosensitive endometrial cancer cell lines derived from a
RT   primary and metastatic tumor of the same patient.";
RL   Gynecol. Oncol. 56:53-62(1995).
//
RX   PubMed=8123477; DOI=10.1038/bjc.1994.87; PMCID=PMC1968845;
RA   Rantanen V., Grenman S.E., Kulmala J., Grenman R.;
RT   "Comparative evaluation of cisplatin and carboplatin sensitivity in
RT   endometrial adenocarcinoma cell lines.";
RL   Br. J. Cancer 69:482-486(1994).
//
RX   PubMed=9887230; DOI=10.1006/gyno.1998.5194;
RA   Rantanen V., Grenman S.E., Kurvinen K., Hietanen S.H., Raitanen M.,
RA   Syrjanen S.M.;
RT   "p53 mutations and presence of HPV DNA do not correlate with
RT   radiosensitivity of gynecological cancer cell lines.";
RL   Gynecol. Oncol. 71:352-358(1998).
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RX   PubMed=17178626; DOI=10.1080/09553000600969812;
RA   Kurvinen K., Rantanen V., Syrjanen S.M., Johansson B.;
RT   "Radiation-induced effects on telomerase in gynecological cancer cell
RT   lines with different radiosensitivity and repair capacity.";
RL   Int. J. Radiat. Biol. 82:859-867(2006).
//