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Cellosaurus BEAS-2B/CYP2A6 (CVCL_WZ49)

[Text version]
Cell line name BEAS-2B/CYP2A6
Synonyms B-2A6
Accession CVCL_WZ49
Resource Identification Initiative To cite this cell line use: BEAS-2B/CYP2A6 (RRID:CVCL_WZ49)
Comments Genetic integration: Method=Transduction; Gene=HGNC; 2610; CYP2A6.
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Transformant: Ad12-SV40 hybrid virus.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0168 (BEAS-2B)
Sex of cell Male
Category Transformed cell line
Publications

PubMed=22743290; DOI=10.1016/j.tox.2012.06.010
Yang X.-J., Lu H.-Y., Li Z.-Y., Bian Q., Qiu L.-L., Li Z., Liu Q.-Z., Li J.-M., Wang X.-R., Wang S.-L.
Cytochrome P450 2A13 mediates aflatoxin B1-induced cytotoxicity and apoptosis in human bronchial epithelial cells.
Toxicology 300:138-148(2012)

PubMed=23602888; DOI=10.1016/j.taap.2013.04.005
Yang X.-J., Zhang Z., Wang X.-C., Wang Y., Zhang X.-M., Lu H.-Y., Wang S.-L.
Cytochrome P450 2A13 enhances the sensitivity of human bronchial epithelial cells to aflatoxin B1-induced DNA damage.
Toxicol. Appl. Pharmacol. 270:114-121(2013)

PubMed=24114584; DOI=10.1002/ijc.28489
Zhang Z., Lu H.-Y., Huan F., Meghan C., Yang X.-J., Wang Y., Wang X.-C., Wang X.-R., Wang S.-L.
Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1.
Int. J. Cancer 134:1539-1548(2014)

Cross-references
Encyclopedic resources Wikidata; Q93425310
Entry history
Entry creation06-Sep-2019
Last entry update10-Sep-2024
Version number8