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Cellosaurus BEAS-2B/CYP2A13 (CVCL_WZ48)

[Text version]
Cell line name BEAS-2B/CYP2A13
Synonyms B-2A13
Accession CVCL_WZ48
Resource Identification Initiative To cite this cell line use: BEAS-2B/CYP2A13 (RRID:CVCL_WZ48)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2010127.
Transfected with: HGNC; 2608; CYP2A13.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transformant: Ad12-SV40 hybrid virus.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0168 (BEAS-2B)
Sex of cell Male
Category Transformed cell line
Publications

PubMed=22743290; DOI=10.1016/j.tox.2012.06.010
Yang X.-J., Lu H.-Y., Li Z.-Y., Bian Q., Qiu L.-L., Li Z., Liu Q.-Z., Li J.-M., Wang X.-R., Wang S.-L.
Cytochrome P450 2A13 mediates aflatoxin B1-induced cytotoxicity and apoptosis in human bronchial epithelial cells.
Toxicology 300:138-148(2012)

Patent=CN102168061B
Wang S.-L., Lu H.-Y., Li Z.-Y., Li J.-M., Yang X.-J.
Human lung cell BEAS-2B/CYP2A13, and preparation method and application thereof.
Patent number CN102168061B, 22-May-2013

PubMed=23602888; DOI=10.1016/j.taap.2013.04.005
Yang X.-J., Zhang Z., Wang X.-C., Wang Y., Zhang X.-M., Lu H.-Y., Wang S.-L.
Cytochrome P450 2A13 enhances the sensitivity of human bronchial epithelial cells to aflatoxin B1-induced DNA damage.
Toxicol. Appl. Pharmacol. 270:114-121(2013)

PubMed=24114584; DOI=10.1002/ijc.28489
Zhang Z., Lu H.-Y., Huan F., Meghan C., Yang X.-J., Wang Y., Wang X.-C., Wang X.-R., Wang S.-L.
Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1.
Int. J. Cancer 134:1539-1548(2014)

Cross-references
Cell line databases/resources CCRID; 4201PAT-CCTCC00427
Encyclopedic resources Wikidata; Q93425306
Entry history
Entry creation06-Sep-2019
Last entry update05-Oct-2023
Version number9