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Cellosaurus HEK293 ABCA4-WT (CVCL_WZ21)

[Text version]
Cell line name HEK293 ABCA4-WT
Accession CVCL_WZ21
Resource Identification Initiative To cite this cell line use: HEK293 ABCA4-WT (RRID:CVCL_WZ21)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; 34; ABCA4.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_U427 (Flp-In-T-REx-293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages http://jhu.technologypublisher.com/technology/23601
Publications

PubMed=26092729; DOI=10.1074/jbc.M115.647685; PMCID=PMC4528136
Sabirzhanova I., Lopes Pacheco M., Rapino D., Grover R., Handa J.T., Guggino W.B., Cebotaru L.
Rescuing trafficking mutants of the ATP-binding cassette protein, ABCA4, with small molecule correctors as a treatment for Stargardt eye disease.
J. Biol. Chem. 290:19743-19755(2015)

Cross-references
Encyclopedic resources Wikidata; Q94092750
Entry history
Entry creation06-Sep-2019
Last entry update10-Sep-2024
Version number9