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Cellosaurus 18605 (CVCL_WZ16)

[Text version]
Cell line name 18605
Accession CVCL_WZ16
Resource Identification Initiative To cite this cell line use: 18605 (RRID:CVCL_WZ16)
Comments Omics: Genome sequenced (low read coverage).
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: Age at sampling and TP53 mutation cDNA coordinates from personal communication of Castillo-Tong, Dan Cacsire.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu188Trpfs*3 (c.560_672del); Zygosity=Unspecified (PubMed=31150822).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Unspecified (PubMed=31150822).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): PubMed=31150822

Markers:
AmelogeninX
CSF1PO12
D1S165612,18.3
D2S133820,25
D3S135814,18
D5S81813
D6S104315
D7S8209,10
D8S117915
D12S39123
D13S31711
D16S53913,14
D18S5115,16
D19S43314,16
D21S1129,30
FGA24
Penta D9,10
Penta E14
TH019
TPOX8
vWA17

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Publications

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J., Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C., Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B., Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WZ16
Encyclopedic resources Wikidata; Q93300434
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number9