Cellosaurus cell line EK_R1 (CVCL

Cellosaurus EK_R1 (CVCL_WZ07)

[Text version]

Cell line name

EK_R1

Accession

CVCL_WZ07

Resource Identification Initiative

To cite this cell line use: EK_R1 (RRID:CVCL_WZ07)

Comments

Omics: Genome sequenced (low read coverage).
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: Age at sampling from personal communication of Castillo-Tong, Dan Cacsire.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys275Tyr (c.824G>A); ClinVar=VCV000215997; Zygosity=Unspecified (PubMed=31150822).

Disease

High grade ovarian serous adenocarcinoma (NCIt: C105555)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_WZ05 ! 8714
CVCL_WZ06 ! 17457

Sex of cell

Female

Age at sampling

56Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31150822

Markers:

Amelogenin	X
CSF1PO	10,12
D1S1656	10,17.3
D2S1338	18,24
D3S1358	17,20
D5S818	12,13
D6S1043	18,19
D7S820	10,12
D8S1179	13,15
D12S391	18,19
D13S317	11,13
D16S539	12,13
D18S51	16,17
D19S433	10,14
D21S11	33.2
FGA	21.2
Penta D	9,10
Penta E	7,16
TH01	9.3
TPOX	8,11
vWA	17

Publications

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J., Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C., Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B., Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WZ07

Encyclopedic resources

Wikidata; Q93539632

Entry history

Entry creation

06-Sep-2019

Last entry update

19-Dec-2024

Version number