Cellosaurus cell line 16471 (CVCL

Cellosaurus 16471 (CVCL_WY99)

[Text version]

Cell line name

16471

Accession

CVCL_WY99

Resource Identification Initiative

To cite this cell line use: 16471 (RRID:CVCL_WY99)

Comments

Omics: Genome sequenced (low read coverage).
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: Age at sampling from personal communication of Castillo-Tong, Dan Cacsire.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.

Sequence variations

Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Trp2626Cys (c.7878G>C); ClinVar=VCV000038125; Zygosity=Unspecified (PubMed=31150822).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr253Pro (c.757A>C); Zygosity=Unspecified (PubMed=31150822).

Disease

High grade ovarian serous adenocarcinoma (NCIt: C105555)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

58Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31150822

Markers:

Amelogenin	X
CSF1PO	12
D1S1656	16.3,17.3
D2S1338	17,24
D3S1358	15
D5S818	13
D6S1043	11,12
D7S820	8
D8S1179	13
D12S391	21,25
D13S317	12
D16S539	12
D18S51	21
D19S433	14
D21S11	28,30.2
FGA	21
Penta D	9
Penta E	10,11
TH01	7
TPOX	11
vWA	15,18

Publications

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J., Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C., Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B., Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WY99

Encyclopedic resources

Wikidata; Q93299835

Entry history

Entry creation

06-Sep-2019

Last entry update

19-Dec-2024

Version number