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Cellosaurus AT5BR (CVCL_WX71)

[Text version]
Cell line name AT5BR
Synonyms AT 5BR; Ataxia Telangiectasia 5 BRighton
Accession CVCL_WX71
Resource Identification Initiative To cite this cell line use: AT5BR (RRID:CVCL_WX71)
Comments Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZT24 ! AT5BR LCL
Sex of cell Female
Age at sampling 30Y
Category Finite cell line
Publications

PubMed=7836839; DOI=10.1080/09553009414551951
Cole J., Arlett C.F.
Cloning efficiency and spontaneous mutant frequency in circulating T-lymphocytes in ataxia-telangiectasia patients.
Int. J. Radiat. Biol. 66:S123-S131(1994)

PubMed=12082606; DOI=10.1038/sj.onc.1205596
Girard P.-M., Riballo E., Begg A.C., Waugh A.P.W., Jeggo P.A.
Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest.
Oncogene 21:4191-4199(2002)

PubMed=15574327; DOI=10.1016/j.molcel.2004.10.029
Riballo E., Kuhne M., Rief N., Doherty A.J., Smith G.C.M., Recio M.-J., Reis C., Dahm K., Fricke A., Krempler A., Parker A.R., Jackson S.P., Gennery A.R., Jeggo P.A., Lobrich M.
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.
Mol. Cell 16:715-724(2004)

PubMed=18079351; DOI=10.1259/bjr/27072321
Arlett C.F., Green M.H.L., Rogers P.B., Lehmann A.R., Plowman P.N.
Minimal ionizing radiation sensitivity in a large cohort of xeroderma pigmentosum fibroblasts.
Br. J. Radiol. 81:51-58(2008)

Cross-references
Encyclopedic resources Wikidata; Q93326404
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number8