ID   Lk9dL
AC   CVCL_WX07
SY   LK9d(L); Lk 9 dL
DR   Wikidata; Q95982402
RX   PubMed=9914777;
RX   PubMed=11011112;
RX   PubMed=11115552;
CC   Sequence variation: Mutation; RGD; 3908; Tsc2; Simple; p.Val1272fs; Zygosity=Heterozygous; Note=Insertion of a 5 kb retrotransposon (from autologous cell line Lk9dR).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Breed/subspecies: Eker x Long-Evans; RS=RS:0000385+RS:0000347.
DI   NCIt; C64111; Carcinoma of the rat kidney
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
OI   CVCL_WX08 ! Lk9dR
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 10-09-24; Version: 7
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RX   PubMed=9914777; DOI=10.1111/j.1349-7006.1998.tb00503.x; PMCID=PMC5921719;
RA   Fukuda T., Hirayama Y., Mitani H., Maeda H., Tsutsumi M., Konishi Y.,
RA   Hino O.;
RT   "Generation of metastatic variants of Eker renal carcinoma cell lines
RT   for experimental investigation of renal cancer metastasis.";
RL   Jpn. J. Cancer Res. 89:1104-1108(1998).
//
RX   PubMed=11011112; DOI=10.1111/j.1349-7006.2000.tb01027.x; PMCID=PMC5926447;
RA   Majima S., Kajino K., Fukuda T., Otsuka F., Hino O.;
RT   "A novel gene 'Niban' upregulated in renal carcinogenesis: cloning by
RT   the cDNA-amplified fragment length polymorphism approach.";
RL   Jpn. J. Cancer Res. 91:869-874(2000).
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RX   PubMed=11115552; DOI=10.3892/ijo.18.1.147;
RA   Okamoto T., Momose S., Hino O.;
RT   "Suppression of cytochrome P450 1A1 and 4A1 gene expression in renal
RT   carcinomas of TSC2 gene mutant (Eker) rats.";
RL   Int. J. Oncol. 18:147-149(2001).
//