ID   ERC-27
AC   CVCL_WX02
SY   Eker Renal Carcinoma-27
DR   Wikidata; Q93541743
RX   CelloPub=CLPUB00521;
RX   PubMed=8419937;
CC   Sequence variation: Mutation; RGD; 3205; Nras; Simple; p.Gly13Val (c.38_39GC>TT); Zygosity=Unspecified (from inference of genetic background of other Eker-derived cell lines).
CC   Sequence variation: Mutation; RGD; 3205; Nras; Simple; p.Val14Ile (c.40G>A); Zygosity=Unspecified (from inference of genetic background of other Eker-derived cell lines).
CC   Sequence variation: Mutation; RGD; 3205; Nras; Simple; p.Ala18Val (c.53C>T); Zygosity=Unspecified (from inference of genetic background of other Eker-derived cell lines).
CC   Sequence variation: Mutation; RGD; 3908; Tsc2; Simple; p.Val1272fs; Zygosity=Heterozygous; Note=Insertion of a 5 kb retrotransposon (from inference of genetic background of other Eker-derived cell lines).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Breed/subspecies: Eker x Long-Evans; RS=RS:0000385+RS:0000347.
DI   NCIt; C64111; Carcinoma of the rat kidney
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Sex unspecified
AG   10-11M
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 10-09-24; Version: 9
//
RX   CelloPub=CLPUB00521;
RA   Freed J.J., Howard S., Lerro A.V., Dodson L.A., Sesok D.,
RA   Knudson A.G. Jr.;
RT   "Hereditary renal tumors in the rat: cell lines from adenocarcinomas
RT   induced by the Eker mutation.";
RL   Proc. Am. Assoc. Cancer Res. 31:317-317(1990).
//
RX   PubMed=8419937; DOI=10.1073/pnas.90.1.327; PMCID=PMC45653;
RA   Hino O., Klein-Szanto A.J.P., Freed J.J., Testa J.R., Brown D.Q.,
RA   Vilensky M., Yeung R.S.W., Tartof K.D., Knudson A.G. Jr.;
RT   "Spontaneous and radiation-induced renal tumors in the Eker rat model
RT   of dominantly inherited cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:327-331(1993).
//