Cellosaurus cell line LB5848-LYMP (CVCL

Cellosaurus LB5848-LYMP (CVCL_WV41)

[Text version]

Cell line name

LB5848-LYMP

Accession

CVCL_WV41

Resource Identification Initiative

To cite this cell line use: LB5848-LYMP (RRID:CVCL_WV41)

Comments

Doubling time: 54 hours (PubMed=30277098); ~50-70 hours (DSMZ=ACC-870).
Derived from site: In situ; Parotid lymph node; UBERON=UBERON_0015857.

Sequence variations

Gene fusion; HGNC; HGNC:990; BCL2 + HGNC; HGNC:5477; IGH; Name(s)=IGH-BCL2 (PubMed=30277098).
Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (PubMed=30277098).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu56Ter (c.166G>T); ClinVar=VCV001329425; Zygosity=Hemizygous (PubMed=30277098).

Disease

High grade B-cell lymphoma with MYC and BCL2 or BCL6 rearrangements (NCIt: C125904)
High grade B-cell lymphoma with MYC and/or BCL2 and/or BCL6 rearrangement (ORDO: Orphanet_480541)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

75Y

Category

Cancer cell line

STR profile

Source(s): DSMZ=ACC-870; PubMed=30277098

Markers:

Amelogenin	X
CSF1PO	11,13
D2S1338	20
D3S1358	15
D5S818	11,12
D7S820	12
D8S1179	13
D13S317	10,12
D16S539	11,12
D18S51	17,22
D19S433	13,14
D21S11	28,30
FGA	20,25
Penta D	12,16
Penta E	10,11
TH01	8,9.3
TPOX	11
vWA	17

Publications

PubMed=30277098; DOI=10.1080/10428194.2018.1508663
Dheur M.-S., Poirel H.A., Ameye G., Tilman G., Saussoy P., Defour J.-P., Camboni A., Van Den Neste E., Coulie P.G., van Baren N.
Characterization of two new high-grade B-cell lymphoma cell lines with MYC and BCL2 rearrangements that are suitable for in vitro drug sensitivity studies.
Leuk. Lymphoma 60:1043-1052(2019)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-870

Cell line databases/resources

cancercelllines; CVCL_WV41
DSMZCellDive; ACC-870

Encyclopedic resources

Wikidata; Q95981506

Entry history

Entry creation

05-Jul-2019

Last entry update

19-Dec-2024

Version number