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Cellosaurus SJG-41 (CVCL_WV20)

[Text version]
Cell line name SJG-41
Synonyms SJG-041
Accession CVCL_WV20
Resource Identification Initiative To cite this cell line use: SJG-41 (RRID:CVCL_WV20)
Comments Omics: Deep exome analysis.
Miscellaneous: STR profile from personal communication of Broad, Simon.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Arg1279His (c.3836G>A); ClinVar=VCV000134930; Zygosity=Heterozygous (CelloPub=CLPUB00517; PubMed=27693639).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr73fs (c.218_219insT); Zygosity=Unspecified (PubMed=27693639).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO10,12
D3S135817,18
D5S81812,13
D7S82010,12
D8S117911,13
D13S31710,11
D16S5399,13
D18S5115,18
D21S1130
FGA22,23
Penta D13,14
Penta E11,15
TH019,9.3
TPOX11,12
vWA17,19

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Publications

CLPUB00518
Goldie S.J.
Studies of FRMD4A in two models of squamous cell carcinoma.
Thesis PhD (2011); University of Cambridge; Cambridge; United Kingdom

PubMed=27693639; DOI=10.1016/j.canlet.2016.09.014; PMCID=PMC5090049
Hayes T.F., Benaich N., Goldie S.J., Sipila K., Ames-Draycott A., Cai W.-J., Yin G.-L., Watt F.M.
Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.
Cancer Lett. 383:106-114(2016)

CLPUB00517
Pritchard A.J.
Correlating genetic change with changes in cell behaviour in squamous cell carcinoma of the head and neck (SCCHN). Focus on inactivating NOTCH1 mutations.
Thesis PhD (2018); King's College London; London; United Kingdom

Cross-references
Encyclopedic resources Wikidata; Q98132631
Entry history
Entry creation05-Jul-2019
Last entry update19-Dec-2024
Version number8