Cellosaurus cell line SJG-33 (CVCL

Cellosaurus SJG-33 (CVCL_WV18)

[Text version]

Cell line name

SJG-33

Synonyms

SJG-033

Accession

CVCL_WV18

Resource Identification Initiative

To cite this cell line use: SJG-33 (RRID:CVCL_WV18)

Comments

Omics: Deep exome analysis.
Miscellaneous: STR profile from personal communication of Broad, Simon.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.

Sequence variations

Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Trp110Ter (c.330G>A) (p.Gly125Arg, c.373G>A); ClinVar=VCV000376303; Zygosity=Unspecified (PubMed=27693639).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Unspecified (PubMed=27693639).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu258Gly (c.773A>G); ClinVar=VCV000406590; Zygosity=Unspecified (PubMed=27693639).

Disease

Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

78Y

Category

Cancer cell line

STR profile

Source(s): Direct_author_submission

Markers:

Amelogenin	X,Y
CSF1PO	12
D3S1358	16
D5S818	10
D7S820	10,11
D8S1179	12,14
D13S317	8,11
D16S539	10,11
D18S51	15,16
D21S11	30
FGA	21
Penta D	9,12
Penta E	15,16
TH01	8,9.3
TPOX	8
vWA	17,18

Publications

CLPUB00518
Goldie S.J.
Studies of FRMD4A in two models of squamous cell carcinoma.
Thesis PhD (2011); University of Cambridge; Cambridge; United Kingdom

PubMed=27693639; DOI=10.1016/j.canlet.2016.09.014; PMCID=PMC5090049
Hayes T.F., Benaich N., Goldie S.J., Sipila K., Ames-Draycott A., Cai W.-J., Yin G.-L., Watt F.M.
Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.
Cancer Lett. 383:106-114(2016)

CLPUB00517
Pritchard A.J.
Correlating genetic change with changes in cell behaviour in squamous cell carcinoma of the head and neck (SCCHN). Focus on inactivating NOTCH1 mutations.
Thesis PhD (2018); King's College London; London; United Kingdom

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WV18

Encyclopedic resources

Wikidata; Q98132618

Entry history

Entry creation

05-Jul-2019

Last entry update

19-Dec-2024

Version number