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Cellosaurus SJG-17 (CVCL_WV11)

[Text version]
Cell line name SJG-17
Synonyms SJG-017
Accession CVCL_WV11
Resource Identification Initiative To cite this cell line use: SJG-17 (RRID:CVCL_WV11)
Comments Omics: Deep exome analysis.
Miscellaneous: STR profile from personal communication of Broad, Simon.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Thr968Met (c.2903C>T); ClinVar=VCV001494610; Zygosity=Heterozygous (CelloPub=CLPUB00517; PubMed=27693639).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu258fs (c.773_774insG); Zygosity=Unspecified (PubMed=27693639).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO11
D3S135814
D5S81811,12
D7S82012
D8S117911,12
D13S3178,12
D16S53912
D18S5118,19
D21S1128,29
FGA21
Penta D11,14
Penta E11,17
TH018,9.3
TPOX8
vWA16,17

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Publications

CLPUB00518
Goldie S.J.
Studies of FRMD4A in two models of squamous cell carcinoma.
Thesis PhD (2011); University of Cambridge; Cambridge; United Kingdom

PubMed=27693639; DOI=10.1016/j.canlet.2016.09.014; PMCID=PMC5090049
Hayes T.F., Benaich N., Goldie S.J., Sipila K., Ames-Draycott A., Cai W.-J., Yin G.-L., Watt F.M.
Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.
Cancer Lett. 383:106-114(2016)

CLPUB00517
Pritchard A.J.
Correlating genetic change with changes in cell behaviour in squamous cell carcinoma of the head and neck (SCCHN). Focus on inactivating NOTCH1 mutations.
Thesis PhD (2018); King's College London; London; United Kingdom

Cross-references
Encyclopedic resources Wikidata; Q98132589
Entry history
Entry creation05-Jul-2019
Last entry update19-Dec-2024
Version number10