| Cell line name |
SJG-8 |
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| Synonyms |
SJG-008 |
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| Accession |
CVCL_WV09 |
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| Resource Identification Initiative |
To cite this cell line use: SJG-8 (RRID:CVCL_WV09) |
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| Comments |
Omics: Deep exome analysis.
Miscellaneous: STR profile from personal communication of Broad, Simon.
Derived from site: In situ; Oral cavity, alveolar ridge; UBERON=UBERON_0004103. |
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| Sequence variations |
- Mutation; HGNC; HGNC:3595; FAT1; Simple; p.Thr677fs (c.2029_2036delACACCAGT); Zygosity=Unspecified (PubMed=27693639).
- Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Asp154His (c.460G>C); Zygosity=Unspecified (PubMed=27693639).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp53Ter (c.159G>A); ClinVar=VCV000420659; Zygosity=Unspecified (PubMed=27693639).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=27693639).
|
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| Disease |
Alveolar ridge squamous cell carcinoma (NCIt: C170774)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Male |
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| Age at sampling |
68Y |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): Direct_author_submission
Markers:| Amelogenin | X,Y |
| CSF1PO | 11,12 |
| D3S1358 | 15,17 |
| D5S818 | 9,12 |
| D7S820 | 9 |
| D8S1179 | 10,13 |
| D13S317 | 11 |
| D16S539 | 10,11 |
| D18S51 | 12,16 |
| D21S11 | 28,30 |
| FGA | 21 |
| Penta D | 8,9 |
| Penta E | 7 |
| TH01 | 9.3 |
| TPOX | 8,11 |
| vWA | 16 |
Run an STR similarity search on this cell line |
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| Publications | CLPUB00518
Goldie S.J.
Studies of FRMD4A in two models of squamous cell carcinoma.
Thesis PhD (2011); University of Cambridge; Cambridge; United Kingdom PubMed=27693639; DOI=10.1016/j.canlet.2016.09.014; PMCID=PMC5090049
Hayes T.F., Benaich N., Goldie S.J., Sipila K., Ames-Draycott A., Cai W.-J., Yin G.-L., Watt F.M.
Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.
Cancer Lett. 383:106-114(2016) CLPUB00517
Pritchard A.J.
Correlating genetic change with changes in cell behaviour in squamous cell carcinoma of the head and neck (SCCHN). Focus on inactivating NOTCH1 mutations.
Thesis PhD (2018); King's College London; London; United Kingdom |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_WV09
|
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| Encyclopedic resources |
Wikidata; Q98132638
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| Entry history |
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| Entry creation | 05-Jul-2019 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 11 |
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