Cellosaurus logo
expasy logo

Cellosaurus MCRIi001-A-2 (CVCL_WU54)

[Text version]
Cell line name MCRIi001-A-2
Synonyms MCRIi001-A-SOX9tdTom; PB001-SOX9tdTom
Accession CVCL_WU54
Resource Identification Initiative To cite this cell line use: MCRIi001-A-2 (RRID:CVCL_WU54)
Comments From: Murdoch Children's Research Institute; Melbourne; Australia.
Population: Caucasian.
Characteristics: Using CRISPR/Cas9 SOX9 has been endogenously tagged at the C-terminus with TdTomato.
Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UK82 (MCRIi001-A)
Children:
CVCL_A9Z3 (MCRIi001-A-3)CVCL_A9Z4 (MCRIi001-A-4)CVCL_ZA74 (MCRIi001-B)
Sex of cell Male
Age at sampling 61Y
Category Induced pluripotent stem cell
Publications

PubMed=31884373; DOI=10.1016/j.scr.2019.101689
Nur Patria Y., Lilianty J., Elefanty A.G., Stanley E.G., Labonne T., Bateman J.F., Lamande S.R.
Generation of a SOX9-tdTomato reporter human iPSC line, MCRIi001-A-2, using CRISPR/Cas9 editing.
Stem Cell Res. 42:101689-101689(2020)

PubMed=32446218; DOI=10.1016/j.scr.2020.101843
Lilianty J., Nur Patria Y., Stanley E.G., Elefanty A.G., Bateman J.F., Lamande S.R.
Generation of a heterozygous COL2A1 (p.R989C) spondyloepiphyseal dysplasia congenita mutation iPSC line, MCRIi001-B, using CRISPR/Cas9 gene editing.
Stem Cell Res. 45:101843-101843(2020)

PubMed=32771907; DOI=10.1016/j.scr.2020.101942
Nur Patria Y., Stenta T., Lilianty J., Rowley L., Stanley E.G., Elefanty A.G., Bateman J.F., Lamande S.R.
CRISPR/Cas9 gene editing of a SOX9 reporter human iPSC line to produce two TRPV4 patient heterozygous missense mutant iPSC lines, MCRIi001-A-3 (TRPV4 p.F273L) and MCRIi001-A-4 (TRPV4 p.P799L).
Stem Cell Res. 48:101942-101942(2020)

Cross-references
Cell line databases/resources hPSCreg; MCRIi001-A-2
Biological sample resources BioSamples; SAMEA5873308
Encyclopedic resources Wikidata; Q95986993
Entry history
Entry creation05-Jul-2019
Last entry update10-Sep-2024
Version number8