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Cellosaurus RS773 (CVCL_WS98)

[Text version]
Cell line name RS773
Synonyms RS-773
Accession CVCL_WS98
Resource Identification Initiative To cite this cell line use: RS773 (RRID:CVCL_WS98)
Comments Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be a B-lymphoblastoid cell line (PubMed=29533902).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Lymph node; UBERON=UBERON_0000029.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=22167753; DOI=10.1182/blood-2011-07-370841
Zocchi M.R., Catellani S., Canevali P., Tavella S., Garuti A., Villaggio B., Zunino A., Gobbi M., Fraternali-Orcioni G., Kunkl A., Ravetti J.L., Boero S., Musso A., Poggi A.
High ERp5/ADAM10 expression in lymph node microenvironment and impaired NKG2D ligands recognition in Hodgkin lymphomas.
Blood 119:1479-1489(2012)

PubMed=27467923; DOI=10.1080/2162402X.2015.1123367; PMCID=PMC4910733
Zocchi M.R., Camodeca C., Nuti E., Rossello A., Vene R., Tosetti F.I., Dapino I., Costa D., Musso A., Poggi A.
ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing.
OncoImmunology 5:e1123367.1-e1123367.10(2016)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Drexler H.G., Pommerenke C., Eberth S., Nagel S.
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Cross-references
Encyclopedic resources Wikidata; Q98129191
Entry history
Entry creation05-Jul-2019
Last entry update10-Sep-2024
Version number6