Cellosaurus cell line ITOC-01 (CVCL

Cellosaurus ITOC-01 (CVCL_WS66)

[Text version]

Cell line name

ITOC-01

Synonyms

Indian Tata memorial centre Oral Cancer-01

Accession

CVCL_WS66

Resource Identification Initiative

To cite this cell line use: ITOC-01 (RRID:CVCL_WS66)

Comments

Population: Indian.
Doubling time: 47.31 hours (PubMed=31164688).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.

Sequence variations

Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Gln1214Ter (c.3640C>T); Zygosity=Unspecified (PubMed=31164688).
Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (PubMed=31164688).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126His (c.376T>C); ClinVar=VCV001734755; Zygosity=Unspecified (PubMed=31164688).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Unspecified (PubMed=31164688).

Disease

Buccal mucosa squamous cell carcinoma (NCIt: C4040)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

28Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31164688

Markers:

Amelogenin	X,Y
CSF1PO	10,12.1
D5S818	10
D7S820	9.3,12
D13S317	10,12
D16S539	13
TH01	5
TPOX	7.3
vWA	15.2,16.1

Publications

PubMed=31164688; DOI=10.1038/s41598-019-44143-0; PMCID=PMC6547758
Pansare K., Gardi N., Kamat S., Dange P., Previn R., Gera P., Kowtal P.K., Amin K., Sarin R.
Establishment and genomic characterization of gingivobuccal carcinoma cell lines with smokeless tobacco associated genetic alterations and oncogenic PIK3CA mutation.
Sci. Rep. 9:8272-8272(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WS66

Encyclopedic resources

Wikidata; Q94325005

Entry history

Entry creation

05-Jul-2019

Last entry update

19-Dec-2024

Version number