ID   LN-2207GS
AC   CVCL_WS27
DR   GEO; GSM1469038
DR   GEO; GSM2794458
DR   GEO; GSM2794459
DR   GEO; GSM2794460
DR   GEO; GSM2889486
DR   Wikidata; Q95982660
RX   PubMed=21097691;
RX   PubMed=22570425;
RX   PubMed=25622821;
CC   Characteristics: Glioma-derived sphere line. Non-tumorigenic in nude mice.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=22570425).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=22570425).
CC   Omics: Array-based CGH.
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: STR profile from personal communication of Gusyatiner, Olga.
CC   Derived from site: In situ; Brain, left parietal lobe; UBERON=UBERON_0002802.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11,12
ST   D10S1248: 14
ST   D12S391: 18,19
ST   D13S317: 11,12
ST   D16S539: 12
ST   D18S51: 11,14
ST   D19S433: 13,14
ST   D1S1656: 17.3
ST   D21S11: 30,31
ST   D22S1045: 15,16
ST   D2S1338: 19,25
ST   D2S441: 11
ST   D3S1358: 14,16
ST   D5S818: 11,12
ST   D7S820: 8
ST   D8S1179: 11,13
ST   DYS391: 10
ST   DYS570: 18
ST   DYS576: 17
ST   FGA: 22,23
ST   Penta D: 12,13
ST   Penta E: 11,12
ST   SE33: 17
ST   TH01: 7,9
ST   TPOX: 8,9
ST   vWA: 16,17
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_S442 ! LN-2207
SX   Male
AG   42Y
CA   Cancer cell line
DT   Created: 05-07-19; Last updated: 19-12-24; Version: 9
//
RX   PubMed=21097691; DOI=10.1158/1078-0432.CCR-10-1931;
RA   Sciuscio D., Diserens A.-C., van Dommelen K., Martinet D., Jones G.,
RA   Janzer R.-C., Pollo C., Hamou M.-F., Kaina B., Stupp R., Levivier M.,
RA   Hegi M.E.;
RT   "Extent and patterns of MGMT promoter methylation in glioblastoma- and
RT   respective glioblastoma-derived spheres.";
RL   Clin. Cancer Res. 17:255-266(2011).
//
RX   PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844;
RA   Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K.,
RA   Hamou M.-F., Delorenzi M., Hegi M.E.;
RT   "DNA fingerprinting of glioma cell lines and considerations on
RT   similarity measurements.";
RL   Neuro-oncol. 14:701-711(2012).
//
RX   PubMed=25622821; DOI=10.1186/s13059-015-0583-7; PMCID=PMC4342872;
RA   Kurscheid S., Bady P., Sciuscio D., Samarzija I., Shay T.,
RA   Vassallo I., Van Criekinge W., Daniel R.T., van den Bent M.J.,
RA   Marosi C., Weller M., Mason W.P., Domany E., Stupp R., Delorenzi M.,
RA   Hegi M.E.;
RT   "Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are
RT   associated with expression of a stem cell related HOX-signature in
RT   glioblastoma.";
RL   Genome Biol. 16:16.1-16.15(2015).
//