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Cellosaurus UCD-Mel-N(Ski+) (CVCL_WS22)

[Text version]
Cell line name UCD-Mel-N(Ski+)
Synonyms UCD(SKI+)
Accession CVCL_WS22
Resource Identification Initiative To cite this cell line use: UCD-Mel-N(Ski+) (RRID:CVCL_WS22)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:10896; SKI.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_WS21 (UCD-Mel-N)
Children:
CVCL_WS23 (UCD-Mel-N(Ski+/Fhl2+))
Category Cancer cell line
Publications

PubMed=10811875; DOI=10.1073/pnas.090097797; PMCID=PMC18535
Xu W.-D., Angelis K., Danielpour D., Haddad M.M., Bischof O., Campisi J., Stavnezer E., Medrano E.E.
Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor.
Proc. Natl. Acad. Sci. U.S.A. 97:5924-5929(2000)

PubMed=14583455
Chen D.-H., Xu W.-D., Bales E.S., Colmenares C., Conacci-Sorrell M., Ishii S., Stavnezer E., Campisi J., Fisher D.E., Ben-Ze'ev A., Medrano E.E.
SKI activates Wnt/beta-catenin signaling in human melanoma.
Cancer Res. 63:6626-6634(2003)

Cross-references
Encyclopedic resources Wikidata; Q98133830
Entry history
Entry creation05-Jul-2019
Last entry update19-Dec-2024
Version number6