Cellosaurus cell line SP212 (CVCL

Cellosaurus SP212 (CVCL_WN80)

[Text version]

Cell line name

SP212

Accession

CVCL_WN80

Resource Identification Initiative

To cite this cell line use: SP212 (RRID:CVCL_WN80)

Comments

Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

Mutation; HGNC; HGNC:10801; SFTPB; Simple; p.Pro121Glufs*95 (c.361delCinsGAA) (121ins2); ClinVar=VCV000013201; Zygosity=Homozygous (PubMed=28965766).

Disease

Pulmonary surfactant metabolism dysfunction-1 (NCIt: C99068)
Neonatal acute respiratory distress due to SP-B deficiency (ORDO: Orphanet_217563)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_WN81 (SP212Corr)

Sex of cell

Female

Age at sampling

Category

Induced pluripotent stem cell

Publications

PubMed=28965766; DOI=10.1016/j.stem.2017.08.014; PMCID=PMC5755620
Jacob A., Morley M., Hawkins F., McCauley K.B., Jean J.-C., Heins H., Na C.-L., Weaver T.E., Vedaie M., Hurley K., Hinds A., Russo S.J., Kook S., Zacharias W., Ochs M., Traber K., Quinton L.J., Crane A.M., Davis B.R., White F.V., Wambach J., Whitsett J.A., Cole F.S., Morrisey E.E., Guttentag S.H., Beers M.F., Kotton D.N.
Differentiation of human pluripotent stem cells into functional lung alveolar epithelial cells.
Cell Stem Cell 21:472-488.e10(2017)

Cross-references

Encyclopedic resources

Wikidata; Q98132805

Entry history

Entry creation

24-May-2019

Last entry update

19-Dec-2024

Version number