Cellosaurus cell line 20842M2 (CVCL

Cross-references
Cell line name	20842M2
Accession	CVCL_WM46
Resource Identification Initiative	To cite this cell line use: 20842M2 (RRID:CVCL_WM46)
Comments	Derived from site: Metastatic; Cutaneous; UBERON=UBERON_0000014.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Leu597Ser (c.1789_1790delCTinsTC); ClinVar=VCV000375942; Zygosity=Unspecified (PubMed=15195137). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly187Ser (c.559G>A); ClinVar=VCV000840399; Zygosity=Unspecified (PubMed=15195137).
Disease	Cutaneous melanoma (NCIt: C3510)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_WM26 ! 20842M1 CVCL_WM19 ! 20842P
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Publications	PubMed=15195137; DOI=10.1038/sj.onc.1207780 Daniotti M., Oggionni M., Ranzani T., Vallacchi V., Campi V., Di Stasi D., Della Torre G., Perrone F., Luoni C., Suardi S., Frattini M., Pilotti S., Anichini A., Tragni G., Parmiani G., Pierotti M.A., Rodolfo M. BRAF alterations are associated with complex mutational profiles in malignant melanoma. Oncogene 23:5968-5977(2004)
Cell line databases/resources	cancercelllines; CVCL_WM46
Encyclopedic resources	Wikidata; Q93301846
Polymorphism and mutation databases	Cosmic; 852220
Entry history
Entry creation	24-May-2019
Last entry update	19-Dec-2024
Version number	9