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Cellosaurus 2211M (CVCL_WM38)

[Text version]
Cell line name 2211M
Accession CVCL_WM38
Resource Identification Initiative To cite this cell line use: 2211M (RRID:CVCL_WM38)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=15195137).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=15195137).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Pro246Ser (c.737C>T); Zygosity=Unspecified (PubMed=15195137).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser127Phe (c.380_381CC>TT); Zygosity=Unspecified (PubMed=15195137).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 41Y
Category Cancer cell line
Publications

PubMed=15195137; DOI=10.1038/sj.onc.1207780
Daniotti M., Oggionni M., Ranzani T., Vallacchi V., Campi V., Di Stasi D., Della Torre G., Perrone F., Luoni C., Suardi S., Frattini M., Pilotti S., Anichini A., Tragni G., Parmiani G., Pierotti M.A., Rodolfo M.
BRAF alterations are associated with complex mutational profiles in malignant melanoma.
Oncogene 23:5968-5977(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WM38
Encyclopedic resources Wikidata; Q93302168
Polymorphism and mutation databases Cosmic; 852213
IARC_TP53; 20613
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number10