ID   HXEX-ALL1
AC   CVCL_WL67
DR   Wikidata; Q94310799
RX   Patent=WO2019144636A1;
RX   PubMed=31168295;
RX   PubMed=31221196;
RX   PubMed=33740980;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2017232.
CC   Population: Chinese.
CC   Doubling time: 26-32 hours (PubMed=31168295).
CC   Omics: Genome sequenced.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): PubMed=31168295; Patent=WO2019144636A1
ST   Amelogenin: X,Y
ST   CSF1PO: 11,13
ST   D10S1248: 13,14
ST   D12S391: 18,20
ST   D13S317: 11
ST   D16S539: 10,11
ST   D18S51: 13,23
ST   D19S433: 14,15
ST   D21S11: 29,33
ST   D2S1338: 18,24
ST   D2S441: 11,11.3
ST   D3S1358: 15
ST   D5S818: 7,10
ST   D6S1043: 12,19
ST   D7S820: 10,12
ST   D8S1179: 13,15
ST   FGA: 24,26
ST   Penta D: 9,11
ST   Penta E: 5,19
ST   TH01: 9
ST   TPOX: 8,9
ST   vWA: 16,17
DI   NCIt; C9140; Childhood B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   6Y
CA   Cancer cell line
DT   Created: 24-05-19; Last updated: 29-06-23; Version: 8
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RX   Patent=WO2019144636A1;
RA   Gu L., Zhu Y.-P., Zhang G., Yang R., Zhang Y.-L., Sun S.-W.;
RT   "Human B-cell acute lymphoblastic leukemia cell line and application
RT   thereof.";
RL   Patent number WO2019144636A1, 01-Aug-2019.
//
RX   PubMed=31168295; DOI=10.1186/s12935-019-0834-x;
RA   Zhu Y.-P., Yang R., Gao J., Zhang Y.-L., Zhang G., Gu L.;
RT   "Establishment and characterization of a novel childhood acute
RT   lymphoblastic leukemia cell line, HXEX-ALL1, with chromosome 9p and
RT   17p deletions.";
RL   Cancer Cell Int. 19:113.1-113.13(2019).
//
RX   PubMed=31221196; DOI=10.1186/s13046-019-1280-2;
RA   Gu L., Zhang G., Zhang Y.-L.;
RT   "A novel method to establish glucocorticoid resistant acute
RT   lymphoblastic leukemia cell lines.";
RL   J. Exp. Clin. Cancer Res. 38:269.1-269.12(2019).
//
RX   PubMed=33740980; DOI=10.1186/s12935-021-01870-7;
RA   Li Y.-Y., Gu L.;
RT   "Establishment and characterization of HXWMF-1: the first mouse
RT   fibroblastic tumor cell line derived from leukemia-associated
RT   fibroblasts.";
RL   Cancer Cell Int. 21:177.1-177.10(2021).
//