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Cellosaurus PANC-1-Cas9-559 (CVCL_WL53)

[Text version]
Cell line name PANC-1-Cas9-559
Accession CVCL_WL53
Resource Identification Initiative To cite this cell line use: PANC-1-Cas9-559 (RRID:CVCL_WL53)
Comments Population: Caucasian.
Characteristics: Transduced with a Cas9-Flag-Neo construct.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0480 (PANC-1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000559

Markers:
AmelogeninX
CSF1PO10,12
D2S133823,24
D3S135817
D5S81811,13
D6S104311,12
D7S8208,10
D8S117914,15
D12S39122
D13S31711
D16S53911
D18S5112
D19S43311,16
D21S1128
FGA21
Penta E7,14
TH017,8
TPOX8,11
vWA15

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Cross-references
Cell line databases/resources cancercelllines; CVCL_WL53
CCRID; 1101HUM-PUMC000559
Encyclopedic resources Wikidata; Q98128479
Entry history
Entry creation24-May-2019
Last entry update10-Sep-2024
Version number12