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Cellosaurus MCF-7/S7 (CVCL_WK28)

[Text version]
Cell line name MCF-7/S7
Synonyms MCF-7 subline 7
Accession CVCL_WK28
Resource Identification Initiative To cite this cell line use: MCF-7/S7 (RRID:CVCL_WK28)
Comments Group: Serum/protein free medium cell line.
Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

Briand P., Lykkesfeldt A.E.
Long-term cultivation of a human breast cancer cell line, MCF-7, in a chemically defined medium. Effect of estradiol.
Anticancer Res. 6:85-90(1986)

Cell line databases/resources cancercelllines; CVCL_WK28
Encyclopedic resources Wikidata; Q95986458
Entry history
Entry creation24-May-2019
Last entry update05-Oct-2023
Version number8