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Cellosaurus PCK-CCL (CVCL_WJ26)

[Text version]
Cell line name PCK-CCL
Accession CVCL_WJ26
Resource Identification Initiative To cite this cell line use: PCK-CCL (RRID:CVCL_WJ26)
Comments Characteristics: Animal model of autosomal recessive polycystic kidney disease (PubMed=16783394).
Doubling time: 28.8 hours (PubMed=16783394).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Cholangiocyte; CL=CL_1000488.
Sequence variations
  • Mutation; RGD; 1308476; Pkhd1; Unexplicit; IVS35-2A>T; Zygosity=Homozygous; Note=Splice acceptor mutation (PubMed=16783394).
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: PCK/CrljCrl-Pkhd1pck/Crl; RS=RS:0001381.
Sex of cell Sex unspecified
Age at sampling 2-3M
Category Spontaneously immortalized cell line
Publications

PubMed=16783394; DOI=10.1038/labinvest.3700448
Muff M.A., Masyuk T.V., Stroope A.J., Huang B.Q., Splinter P.L., Lee S.-O., LaRusso N.F.
Development and characterization of a cholangiocyte cell line from the PCK rat, an animal model of autosomal recessive polycystic kidney disease.
Lab. Invest. 86:940-950(2006)

Cross-references
Encyclopedic resources Wikidata; Q98128523
Entry history
Entry creation24-May-2019
Last entry update10-Sep-2024
Version number9