Cellosaurus cell line HCCLM3-GFP-LC3 (CVCL

Cellosaurus HCCLM3-GFP-LC3 (CVCL_WJ13)

Cross-references
Cell line name	HCCLM3-GFP-LC3
Accession	CVCL_WJ13
Resource Identification Initiative	To cite this cell line use: HCCLM3-GFP-LC3 (RRID:CVCL_WJ13)
Comments	Group: Patented cell line. Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2010102. Population: Chinese. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6838; MAP1LC3A. Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Sequence variations	Mutation; HGNC; HGNC:14310; BRD7; Simple; p.Glu277Glyfs18 (c.830_831delAG); Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:23177; KEAP1; Simple; p.Pro445Glnfs13 (c.1334delC); Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu51Ter (c.151G>T); ClinVar=VCV000568781; Zygosity=Unspecified (from parent cell line).
Disease	Adult hepatocellular carcinoma (NCIt: C7956) Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_6832 (HCCLM3)
Sex of cell	Male
Age at sampling	39Y
Category	Cancer cell line
Publications	Patent=CN102115730A Fan J., Shi Y.-H., Peng Y.-F., Ding Z.-B. High metastatic potential hepatoma cell line capable of steady autophagy indication, and establishment method and application method thereof. Patent number CN102115730A, 06-Jul-2011 PubMed=24058558; DOI=10.1371/journal.pone.0074407; PMCID=PMC3772859 Peng Y.-F., Shi Y.-H., Shen Y.-H., Ding Z.-B., Ke A.-W., Zhou J., Qiu S.-J., Fan J. Promoting colonization in metastatic HCC cells by modulation of autophagy. PLoS ONE 8:E74407-E74407(2013)
Cell line databases/resources	cancercelllines; CVCL_WJ13 CCRID; 4201PAT-CCTCC00405
Encyclopedic resources	Wikidata; Q93984342
Entry history
Entry creation	24-May-2019
Last entry update	19-Dec-2024
Version number	10