Cellosaurus HGELN (CVCL_WI90)
| Cell line name | HGELN |
|---|---|
| Synonyms | HeLa GAL4RE-ERE Luciferase-Neo |
| Accession | CVCL_WI90 |
| Resource Identification Initiative | To cite this cell line use: HGELN (RRID:CVCL_WI90) |
| Comments | Population: African American. Biotechnology: Used in a bioluminescent bioassay to quantitatively measure estrogenic compounds. Characteristics: The luciferase reporter gene is under the control of an estrogen-responsive element from the beta-globin promoter. Characteristics: Transfected with the DNA-binding domain (DBD) of GAL4 fused to the ligand-binding domain (LBD) of ESR1 (GAL4-ER). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3467; ESR1 (Note=Ligand-binding domain). Genetic integration: Method=Transfection; Gene=UniProtKB; P04386; Yeast GAL4 (Note=With p.Ile148_Glu881del = DNA-binding domain). Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0030 (HeLa) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=10492897; DOI=10.1016/S0048-9697(99)00178-3 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q94204125 |
| Entry history | |
| Entry creation | 24-May-2019 |
| Last entry update | 19-Dec-2024 |
| Version number | 9 |