ID   HELN(alpha)
AC   CVCL_WI88
SY   HELN ERalpha; HELN-ERalpha
DR   Wikidata; Q94101425
RX   PubMed=10492897;
RX   PubMed=11312541;
CC   Population: African American.
CC   Biotechnology: Used in a bioluminescent bioassay to quantitatively measure estrogenic compounds.
CC   Characteristics: The luciferase reporter gene is under the control of an estrogen-responsive element from the beta-globin promoter.
CC   Transfected with: HGNC; 3467; ESR1.
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_WI87 ! HELN
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 24-05-19; Last updated: 05-10-23; Version: 9
//
RX   PubMed=10492897; DOI=10.1016/S0048-9697(99)00178-3;
RA   Balaguer P., Francois F., Comunale F., Fenet H., Boussioux A.-M.,
RA   Pons M., Nicolas J.-C., Casellas C.;
RT   "Reporter cell lines to study the estrogenic effects of
RT   xenoestrogens.";
RL   Sci. Total Environ. 233:47-56(1999).
//
RX   PubMed=11312541; DOI=10.1002/bio.630;
RA   Balaguer P., Boussioux A.-M., Demirpence E., Nicolas J.-C.;
RT   "Reporter cell lines are useful tools for monitoring biological
RT   activity of nuclear receptor ligands.";
RL   Luminescence 16:153-158(2001).
//