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Cellosaurus IR-M4 (CVCL_WI74)

[Text version]
Cell line name IR-M4
Accession CVCL_WI74
Resource Identification Initiative To cite this cell line use: IR-M4 (RRID:CVCL_WI74)
Comments Population: Latino or Hispanic.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:6091; INSR; Simple; p.Glu151Ter (c.451G>T) (E124X); Zygosity=Homozygous (PubMed=26831110).
Disease Donohue syndrome (NCIt: C84676)
Leprechaunism (ORDO: Orphanet_508)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9Y54 (GM20327)
Sex of cell Female
Age at sampling 2M
Category Induced pluripotent stem cell
Publications

PubMed=26831110; DOI=10.1073/pnas.1525665113; PMCID=PMC4763759
Iovino S., Burkart A.M., Warren L., Patti M.-E., Kahn C.R.
Myotubes derived from human-induced pluripotent stem cells mirror in vivo insulin resistance.
Proc. Natl. Acad. Sci. U.S.A. 113:1889-1894(2016)

Cross-references
Cell line databases/resources SKIP; SKIP000915
Encyclopedic resources Wikidata; Q94323674
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number9