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Cellosaurus MOLM/AZA-1 (CVCL_WI20)

[Text version]
Cell line name MOLM/AZA-1
Accession CVCL_WI20
Resource Identification Initiative To cite this cell line use: MOLM/AZA-1 (RRID:CVCL_WI20)
Comments Population: Japanese.
Doubling time: 17 hours (PubMed=28052028).
Selected for resistance to: ChEBI; CHEBI:2038; 5-azacytidine (5-azaC).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
  • Mutation; HGNC; 3765; FLT3; Unexplicit; Internal tandem duplication (FLT3-ITD); ClinVar=VCV000016270; Zygosity=Unspecified (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Myelodysplastic syndrome (NCIt: C3247)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2119 (MOLM-13)
Sex of cell Male
Age at sampling 20Y
Category Cancer cell line
Publications

PubMed=28052028; DOI=10.18632/oncotarget.14342; PMCID=PMC5355301
Hur E.-H., Jung S.-H., Goo B.-K., Moon J., Choi Y., Choi D.R., Chung Y.-J., Lee J.-H.
Establishment and characterization of hypomethylating agent-resistant cell lines, MOLM/AZA-1 and MOLM/DEC-5.
Oncotarget 8:11748-11762(2017)

Cross-references
Encyclopedic resources Wikidata; Q95990499
Entry history
Entry creation24-May-2019
Last entry update29-Jun-2023
Version number9