ID   OUMS-24F/p53
AC   CVCL_WH83
DR   Wikidata; Q98128397
RX   DOI=10.11418/jtca1981.12.4_313;
RX   PubMed=8148305;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11998; TP53 (Note=With p.Arg273His).
CC   Transformant: ChEBI; CHEBI_16907; 4-nitroquinoline N-oxide (4NQO).
CC   Derived from site: In situ; Fetus; UBERON=UBERON_0000323.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B370 ! OUMS-24F
SX   Female
AG   6FW
CA   Transformed cell line
DT   Created: 24-05-19; Last updated: 19-12-24; Version: 10
//
RX   DOI=10.11418/jtca1981.12.4_313;
RA   Namba M., Bai L., Kano Y., Sugihara S., Miyazaki M.;
RT   "Multistep malignant transformation of human cells: immortalization of
RT   human fibroblasts by treatment with 60Co gamma rays and 4-nitroquinoline
RT   1-oxide, and their malignant transformation with the ras oncogene.";
RL   Tissue Cult. Res. Commun. 12:313-318(1993).
//
RX   PubMed=8148305;
RA   Namba M., Iijima M., Kondo T., Jahan I., Mihara K.;
RT   "Immortalization of normal human cells is a multistep process and a
RT   rate limiting step of neoplastic transformation of the cells.";
RL   Hum. Cell 6:253-259(1993).
//