ID   CAEP [Human lung carcinoma]
AC   CVCL_WH08
DR   IARC_TP53; 13988
DR   Wikidata; Q93441396
RX   PubMed=9809028;
RX   PubMed=10574245;
RX   PubMed=10841287;
RX   PubMed=26919099;
CC   Doubling time: ~50 hours (PubMed=9809028).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg209Ter (c.625A>T); Zygosity=Unspecified (PubMed=10841287).
CC   Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
DI   NCIt; C3493; Lung squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 24-05-19; Last updated: 19-12-24; Version: 6
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RX   PubMed=9809028; DOI=10.1016/S0165-4608(98)00076-4;
RA   Gasperi-Campani A., Roncuzzi L., Ricotti L., Lenzi L., Gruppioni R.,
RA   Sensi A., Zini N., Zoli W., Amadori D.;
RT   "Molecular and biological features of two new human squamous and
RT   adenocarcinoma of the lung cell lines.";
RL   Cancer Genet. Cytogenet. 107:11-20(1998).
//
RX   PubMed=10574245; DOI=10.1038/sj.bjc.6690737; PMCID=PMC2362882;
RA   Zoli W., Ricotti L., Dal Susino M., Barzanti F., Frassineti G.L.,
RA   Folli S., Tesei A., Bacci F., Amadori D.;
RT   "Docetaxel and gemcitabine activity in NSCLC cell lines and in primary
RT   cultures from human lung cancer.";
RL   Br. J. Cancer 81:609-615(1999).
//
RX   PubMed=10841287;
RA   Calistri D., Barzanti F., Dal Susino M., Fedriga R., Saragoni L.,
RA   Bernardi L., Ricotti L., Zoli W.;
RT   "Correlation between p53 gene mutations and p53 protein accumulation
RT   evaluated by different methodologies.";
RL   J. Biol. Regul. Homeost. Agents 14:120-127(2000).
//
RX   PubMed=26919099; DOI=10.18632/oncotarget.7575; PMCID=PMC4951299;
RA   Arienti C., Zanoni M., Pignatta S., Del Rio A., Carloni S.,
RA   Tebaldi M., Tedaldi G., Tesei A.;
RT   "Preclinical evidence of multiple mechanisms underlying trastuzumab
RT   resistance in gastric cancer.";
RL   Oncotarget 7:18424-18439(2016).
//