ID   KKP
AC   CVCL_WH05
DR   cancercelllines; CVCL_WH05
DR   Wikidata; Q94340154
RX   PubMed=9689929;
RX   PubMed=10841287;
RX   PubMed=26919099;
CC   Doubling time: 48 hours (PubMed=9689929); 30 hours (PubMed=26919099).
CC   Sequence variation: Mutation; HGNC; 3430; ERBB2; Simple; p.Ser903Arg (c.2709T>G); Zygosity=Unspecified (PubMed=26919099).
CC   Sequence variation: Mutation; HGNC; 3430; ERBB2; Simple; p.Pro1170Ala (c.3508C>G); ClinVar=VCV000134082; Zygosity=Unspecified (PubMed=26919099).
CC   Sequence variation: Mutation; HGNC; 3431; ERBB3; Simple; p.Thr757Lys (c.2270C>A); Zygosity=Unspecified (PubMed=26919099).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4004; Gastric adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   63Y
CA   Cancer cell line
DT   Created: 24-05-19; Last updated: 05-10-23; Version: 8
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RX   PubMed=9689929; DOI=10.1016/S0165-4608(98)00010-7;
RA   Zoli W., Ricotti L., Lenzi L., Roncuzzi L., Zini N., Amadori D.,
RA   Gruppioni R., Sensi A., Gasperi-Campani A.;
RT   "Molecular genetics and in vitro sensitivity of a new human cell line,
RT   KKP, from a gastric adenocarcinoma.";
RL   Cancer Genet. Cytogenet. 105:43-49(1998).
//
RX   PubMed=10841287;
RA   Calistri D., Barzanti F., Dal Susino M., Fedriga R., Saragoni L.,
RA   Bernardi L., Ricotti L., Zoli W.;
RT   "Correlation between p53 gene mutations and p53 protein accumulation
RT   evaluated by different methodologies.";
RL   J. Biol. Regul. Homeost. Agents 14:120-127(2000).
//
RX   PubMed=26919099; DOI=10.18632/oncotarget.7575; PMCID=PMC4951299;
RA   Arienti C., Zanoni M., Pignatta S., Del Rio A., Carloni S.,
RA   Tebaldi M., Tedaldi G., Tesei A.;
RT   "Preclinical evidence of multiple mechanisms underlying trastuzumab
RT   resistance in gastric cancer.";
RL   Oncotarget 7:18424-18439(2016).
//