Cellosaurus logo
expasy logo

Cellosaurus HSC-5 [Human OCSCC] (CVCL_W943)

[Text version]
Cell line name HSC-5 [Human OCSCC]
Synonyms HSC5
Accession CVCL_W943
Resource Identification Initiative To cite this cell line use: HSC-5 [Human OCSCC] (RRID:CVCL_W943)
Comments Population: Japanese.
Sequence variations
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=1570156
Sakai E., Tsuchida N.
Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.
Oncogene 7:927-933(1992)

PubMed=17052259; DOI=10.1111/j.1349-7006.2006.00343.x; PMCID=PMC11160012
Kozaki K.-i., Imoto I., Pimkhaokham A., Hasegawa S., Tsuda H., Omura K., Inazawa J.
PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma.
Cancer Sci. 97:1351-1358(2006)

PubMed=17599052; DOI=10.1038/sj.onc.1210589
Suzuki E., Imoto I., Pimkhaokham A., Nakagawa T., Kamata N., Kozaki K.-i., Amagasa T., Inazawa J.
PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.
Oncogene 26:7921-7932(2007)

PubMed=18097548; DOI=10.3892/ijo.32.1.101
Murugan A.K., Hong N.T., Fukui Y., Munirajan A.K., Tsuchida N.
Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.
Int. J. Oncol. 32:101-111(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W943
CGH-DB; 366-2
Encyclopedic resources Wikidata; Q54896402
Polymorphism and mutation databases Cosmic; 930333
Cosmic; 1046032
Cosmic; 1123041
IARC_TP53; 1103
Entry history
Entry creation17-Jul-2014
Last entry update19-Dec-2024
Version number12