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Cellosaurus CUTC5 (CVCL_W916)

[Text version]
Cell line name CUTC5
Synonyms PE030810
Accession CVCL_W916
Resource Identification Initiative To cite this cell line use: CUTC5 (RRID:CVCL_W916)
Comments Doubling time: 29 hours (PubMed=30733375).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
Disease Thyroid gland papillary carcinoma (NCIt: C4035)
Differentiated thyroid carcinoma (ORDO: Orphanet_146)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 73Y
Category Cancer cell line
STR profile Source(s): PubMed=30733375; PubMed=30737244

Markers:
AmelogeninX
CSF1PO11,12
D3S135814,18
D5S81811,12
D7S82010
D8S117912,13
D13S31712,14
D16S5399,12
D18S5112,13
D21S1127,31.2
FGA22.2,26
TH016,8
TPOX9,11
vWA17

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Publications

PubMed=23833040; DOI=10.1210/jc.2013-2383; PMCID=PMC3763971
Landa I., Ganly I., Chan T.A., Mitsutake N., Matsuse M., Ibrahimpasic T., Ghossein R.A., Fagin J.A.
Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.
J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)

PubMed=30733375; DOI=10.1158/1541-7786.MCR-18-1026; PMCID=PMC6711777
Schweppe R.E., Pozdeyev N., Pike L.A., Korch C.T., Zhou Q., Sams S.B., Sharma V., Pugazhenthi U., Raeburn C.D., Albuja-Cruz M.B., Reigan P., LaBarbera D.V., Landa-Lopez I., Knauf J.A., Fagin J.A., Haugen B.R.
Establishment and characterization of four novel thyroid cancer cell lines and PDX models expressing the RET/PTC1 rearrangement, BRAFV600E, or RASQ61R as drivers.
Mol. Cancer Res. 17:1036-1048(2019)

PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953; PMCID=PMC6522280
Landa I., Pozdeyev N., Korch C.T., Marlow L.A., Smallridge R.C., Copland J.A. 3rd, Henderson Y.C., Lai S.Y., Clayman G.L., Onoda N., Tan A.-C., Garcia-Rendueles M.E.R., Knauf J.A., Haugen B.R., Fagin J.A., Schweppe R.E.
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W916
Encyclopedic resources Wikidata; Q54946886
Polymorphism and mutation databases Cosmic; 2054115
Entry history
Entry creation17-Jul-2014
Last entry update19-Dec-2024
Version number15