ID   OCUT-2C
AC   CVCL_W915
SY   Ocut-2C; OCUT2C; Osaka City University Thyroid-2C
DR   cancercelllines; CVCL_W915
DR   CCRID; 3101HUMSCSP553
DR   Cosmic; 2054108
DR   Wikidata; Q54931847
RX   PubMed=23833040;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23833040).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (PubMed=23833040).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Homozygous; Note=In promoter (PubMed=23833040).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): CCRID=3101HUMSCSP553
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 9
ST   D5S818: 13
ST   D7S820: 11
ST   TH01: 6,7
ST   TPOX: 11
ST   vWA: 14,18
DI   NCIt; C3878; Thyroid gland anaplastic carcinoma
DI   ORDO; Orphanet_142; Anaplastic thyroid carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9814 ! OCUT-2
SX   Female
AG   81Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 17
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RX   PubMed=23833040; DOI=10.1210/jc.2013-2383; PMCID=PMC3763971;
RA   Landa I., Ganly I., Chan T.A., Mitsutake N., Matsuse M.,
RA   Ibrahimpasic T., Ghossein R.A., Fagin J.A.;
RT   "Frequent somatic TERT promoter mutations in thyroid cancer: higher
RT   prevalence in advanced forms of the disease.";
RL   J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013).
//