Cell line name |
LUCC3 |
Accession |
CVCL_W894 |
Resource Identification Initiative |
To cite this cell line use: LUCC3 (RRID:CVCL_W894) |
Comments |
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. |
Sequence variations |
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Glu507Gln (c.1519G>C); Zygosity=Unspecified (PubMed=24367658).
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg557Pro (c.1670G>C); Zygosity=Unspecified (PubMed=24367658).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=24035680).
|
Disease |
Bladder carcinoma (NCIt: C4912) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Sex of cell |
Sex unspecified |
Age at sampling |
Age unspecified |
Category |
Cancer cell line |
Publications | PubMed=19802009; DOI=10.1038/onc.2009.315 Askham J.M., Platt F.M., Chambers P.A., Snowden H., Taylor C.F., Knowles M.A. AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K. Oncogene 29:150-155(2010) PubMed=24367658; DOI=10.1371/journal.pone.0084411; PMCID=PMC3867501 Ross R.L., Burns J.E., Taylor C.F., Mellor P., Anderson D.H., Knowles M.A. Identification of mutations in distinct regions of p85 alpha in urothelial cancer. PLoS ONE 8:E84411-E84411(2013) PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057 Hurst C.D., Platt F.M., Knowles M.A. Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine. Eur. Urol. 65:367-369(2014) PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350 Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D. Systematic review: characteristics and preclinical uses of bladder cancer cell lines. Bladder Cancer 4:169-183(2018) |
Cross-references |
Encyclopedic resources |
Wikidata; Q54903249
|
Polymorphism and mutation databases |
Cosmic; 1286010
Cosmic; 2050451
Cosmic; 2686103
|
Entry history |
Entry creation | 17-Jul-2014 |
Last entry update | 19-Dec-2024 |
Version number | 10 |
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