ID   ALL/MIK
AC   CVCL_W883
SY   ALL:MIK
DR   Wikidata; Q54749233
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=1884023;
RX   PubMed=8167560;
RX   PubMed=10071072;
RX   PubMed=10576511;
CC   Population: Japanese.
CC   Doubling time: 36-48 hours (PubMed=8167560).
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 1 fused to ABL1 exon 2 (e1a2 transcript) (PubMed=8167560; PubMed=10071072; PubMed=10576511).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C114819; Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
DI   ORDO; Orphanet_585909; B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   74Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 17
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RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=1884023; DOI=10.1182/blood.V78.6.1574.1574;
RA   Okabe M., Kunieda Y., Sugiwura T., Tanaka M., Miyagishima T., Saiki I.,
RA   Minagawa T., Kurosawa M., Itaya T., Miyazaki T.;
RT   "Inhibitory effect of interleukin-4 on the in vitro growth of
RT   Ph1-positive acute lymphoblastic leukemia cells.";
RL   Blood 78:1574-1580(1991).
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RX   PubMed=8167560; DOI=10.3109/10428199409059601;
RA   Higa T., Okabe M., Kunieda Y., Kodama S., Itaya T., Kurosawa M.,
RA   Sakurada K., Maekawa I., Shoji M., Kasai M., Miyazaki T.;
RT   "Establishment and characterization of a new Ph1-positive ALL cell
RT   line (ALL/MIK) presenting bcr gene rearrangement on bcr-2 and
RT   ALL-type bcr/abl transcript: suggestion of in vitro differentiation to
RT   monocytoid lineage.";
RL   Leuk. Lymphoma 12:287-296(1994).
//
RX   PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4;
RA   Drexler H.G., MacLeod R.A.F., Uphoff C.C.;
RT   "Leukemia cell lines: in vitro models for the study of Philadelphia
RT   chromosome-positive leukemia.";
RL   Leuk. Res. 23:207-215(1999).
//
RX   PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9;
RA   Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.;
RT   "ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.";
RL   Leuk. Res. 23:1055-1060(1999).
//