ID   PC-53A
AC   CVCL_W803
SY   PC53A
DR   ArrayExpress; E-MTAB-11038
DR   ArrayExpress; E-MTAB-11039
DR   Wikidata; Q54938460
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=2314113;
RX   PubMed=34940123;
CC   Characteristics: Established at the final progression phase.
CC   Doubling time: 70-80 hours (PubMed=2314113).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=34940123).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (PubMed=34940123).
CC   Sequence variation: Mutation; HGNC; HGNC:8619; PAX5; Simple; p.Arg38His (c.113G>A); Zygosity=Heterozygous (PubMed=34940123).
CC   Omics: Array-based CGH.
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C9143; Adult B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_W802 ! PC-53
SX   Female
AG   34Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 10
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=2314113; DOI=10.1016/0145-2126(90)90047-D;
RA   Tarella C., Pregno P., Gallo E., Caracciolo D., Stefani S.,
RA   Barletta C., Lanfrancone L., Ferrero D.;
RT   "Establishment from an adult leukemic patient of two novel precursor B
RT   cell lines with different growth modality.";
RL   Leuk. Res. 14:177-184(1990).
//
RX   PubMed=34940123; DOI=10.3390/cimb43030149; PMCID=PMC8929001;
RA   Quentmeier H., Pommerenke C., Drexler H.G.;
RT   "Molecular genetics of pre-B acute lymphoblastic leukemia sister cell
RT   lines during disease progression.";
RL   Curr. Issues Mol. Biol. 43:2147-2156(2021).
//