ID   EW36
AC   CVCL_W742
SY   Ew36; EW-36; EW 36
DR   Cosmic; 931104
DR   Wikidata; Q54833005
RX   PubMed=1325212;
RX   PubMed=2052620;
RX   PubMed=3080238;
RX   PubMed=3100061;
RX   PubMed=6243721;
RX   PubMed=6243722;
RX   PubMed=6265077;
RX   PubMed=6286763;
RX   PubMed=7757991;
RX   PubMed=8176200;
RX   PubMed=8402660;
RX   PubMed=8515068;
RX   PubMed=8568269;
RX   PubMed=9192833;
RX   PubMed=9473234;
RX   PubMed=9973220;
CC   Virology: EBV-negative.
CC   Doubling time: 24 hours (PubMed=8402660).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C3457; B-cell non-Hodgkin lymphoma
DI   ORDO; Orphanet_171915; B-cell non-Hodgkin lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 12
//
RX   PubMed=1325212; DOI=10.1182/blood.V80.5.1289.1289;
RA   Benjamin D., Knobloch T.J., Dayton M.A.;
RT   "Human B-cell interleukin-10: B-cell lines derived from patients with
RT   acquired immunodeficiency syndrome and Burkitt's lymphoma
RT   constitutively secrete large quantities of interleukin-10.";
RL   Blood 80:1289-1298(1992).
//
RX   PubMed=2052620; DOI=10.1073/pnas.88.12.5413; PMCID=PMC51883;
RA   Gaidano G., Ballerini P., Gong J.Z., Inghirami G., Neri A.,
RA   Newcomb E.W., Magrath I.T., Knowles D.M., Dalla-Favera R.;
RT   "p53 mutations in human lymphoid malignancies: association with
RT   Burkitt lymphoma and chronic lymphocytic leukemia.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:5413-5417(1991).
//
RX   PubMed=3080238;
RA   Sieverts H., Alabaster O., Goldschmidts W., Magrath I.T.;
RT   "Expression of surface antigens during the cell cycle in different
RT   growth phases of American and African Burkitt's lymphoma cell lines.";
RL   Cancer Res. 46:1182-1188(1986).
//
RX   PubMed=3100061; DOI=10.1016/0008-8749(86)90099-7;
RA   Benjamin D., Bazar L.S., Wallace B., Jacobson R.J.;
RT   "Heterogeneity of B-cell growth factor receptor reactivity in healthy
RT   donors and in patients with chronic lymphatic leukemia: relationship
RT   to B-cell-derived lymphokines.";
RL   Cell. Immunol. 103:394-408(1986).
//
RX   PubMed=6243721; DOI=10.1093/jnci/64.3.465;
RA   Magrath I.T., Pizzo P.A., Whang-Peng J., Douglass E.C., Alabaster O.,
RA   Gerber P., Freeman C.B., Novikovs L.;
RT   "Characterization of lymphoma-derived cell lines: comparison of cell
RT   lines positive and negative for Epstein-Barr virus nuclear antigen. I.
RT   Physical, cytogenetic, and growth characteristics.";
RL   J. Natl. Cancer Inst. 64:465-476(1980).
//
RX   PubMed=6243722; DOI=10.1093/jnci/64.3.477;
RA   Magrath I.T., Freeman C.B., Pizzo P.A., Gadek J., Jaffe E.S.,
RA   Santaella M., Hammer C., Frank M.M., Reaman G., Novikovs L.;
RT   "Characterization of lymphoma-derived cell lines: comparison of cell
RT   lines positive and negative for Epstein-Barr virus nuclear antigen.
RT   II. Surface markers.";
RL   J. Natl. Cancer Inst. 64:477-483(1980).
//
RX   PubMed=6265077;
RA   Pizzo P.A., Chattopadhyay S.K., Magrath I.T., Del Giacco E.,
RA   Sherrick D., Gray T.E.;
RT   "Examination of Epstein-Barr virus and C-type proviral sequences in
RT   American and African lymphomas and derivative cell lines.";
RL   Cancer Res. 41:3165-3171(1981).
//
RX   PubMed=6286763; DOI=10.4049/jimmunol.129.3.1336;
RA   Benjamin D., Magrath I.T., Maguire R.T., Janus C., Todd-Kulikowsk H.D.,
RA   Parsons R.G.;
RT   "Immunoglobulin secretion by cell lines derived from African and
RT   American undifferentiated lymphomas of Burkitt's and non-Burkitt's
RT   type.";
RL   J. Immunol. 129:1336-1342(1982).
//
RX   PubMed=7757991;
RA   Bae I., Fan S.-J., Bhatia K.G., Kohn K.W., Fornace A.J. Jr.,
RA   O'Connor P.M.;
RT   "Relationships between G1 arrest and stability of the p53 and
RT   p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma
RT   cells.";
RL   Cancer Res. 55:2387-2393(1995).
//
RX   PubMed=8176200; DOI=10.4049/jimmunol.152.10.4749;
RA   Benjamin D., Sharma V., Knobloch T.J., Armitage R.J., Dayton M.A.,
RA   Goodwin R.G.;
RT   "B cell IL-7. Human B cell lines constitutively secrete IL-7 and
RT   express IL-7 receptors.";
RL   J. Immunol. 152:4749-4757(1994).
//
RX   PubMed=8402660;
RA   O'Connor P.M., Jackman J., Jondle D., Bhatia K.G., Magrath I.T.,
RA   Kohn K.W.;
RT   "Role of the p53 tumor suppressor gene in cell cycle arrest and
RT   radiosensitivity of Burkitt's lymphoma cell lines.";
RL   Cancer Res. 53:4776-4780(1993).
//
RX   PubMed=8515068; DOI=10.4049/jimmunol.150.12.5418;
RA   Jain V.K., Judde J.-G., Max E.E., Magrath I.T.;
RT   "Variable IgH chain enhancer activity in Burkitt's lymphomas suggests
RT   an additional, direct mechanism of c-myc deregulation.";
RL   J. Immunol. 150:5418-5428(1993).
//
RX   PubMed=8568269; DOI=10.4049/jimmunol.156.4.1626;
RA   Benjamin D., Sharma V., Kubin M., Klein J.L., Sartori A., Holliday J.,
RA   Trinchieri G.;
RT   "IL-12 expression in AIDS-related lymphoma B cell lines.";
RL   J. Immunol. 156:1626-1637(1996).
//
RX   PubMed=9192833;
RA   Cherney B.W., Bhatia K.G., Sgadari C., Gutierrez M.I., Mostowski H.S.,
RA   Pike S.E., Gupta G., Magrath I.T., Tosato G.;
RT   "Role of the p53 tumor suppressor gene in the tumorigenicity of
RT   Burkitt's lymphoma cells.";
RL   Cancer Res. 57:2508-2515(1997).
//
RX   PubMed=9473234; DOI=10.1182/blood.V91.5.1680;
RA   Klangby U., Okan I., Magnusson K.P., Wendland M., Lind P., Wiman K.G.;
RT   "p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a
RT   mRNA and protein expression in Burkitt's lymphoma.";
RL   Blood 91:1680-1687(1998).
//
RX   PubMed=9973220;
RA   Gutierrez M.I., Cherney B.W., Hussain A., Mostowski H.S., Tosato G.,
RA   Magrath I.T., Bhatia K.G.;
RT   "Bax is frequently compromised in Burkitt's lymphomas with
RT   irreversible resistance to Fas-induced apoptosis.";
RL   Cancer Res. 59:696-703(1999).
//