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Cellosaurus HH543-5 (CVCL_W741)

[Text version]
Cell line name HH543-5
Accession CVCL_W741
Resource Identification Initiative To cite this cell line use: HH543-5 (RRID:CVCL_W741)
Comments Population: African; Nigerian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr163His (c.487T>C); ClinVar=VCV000376680; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu287Ter (c.859G>T); Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2676 (P3HR-1)
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=6302703; DOI=10.1073/pnas.80.9.2762; PMCID=PMC393908
Rabson M., Heston L., Miller G.
Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells.
Proc. Natl. Acad. Sci. U.S.A. 80:2762-2766(1983)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W741
Encyclopedic resources Wikidata; Q54887480
Entry history
Entry creation17-Jul-2014
Last entry update19-Dec-2024
Version number17