Cellosaurus logo
expasy logo

Cellosaurus KH88 C2F8 (CVCL_W721)

[Text version]
Cell line name KH88 C2F8
Synonyms KH88-C2F8; KH88 subclone C2F8; C2F8
Accession CVCL_W721
Resource Identification Initiative To cite this cell line use: KH88 C2F8 (RRID:CVCL_W721)
Comments Population: Japanese.
Doubling time: 20-26 hours (PubMed=8289484).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (PubMed=10071072; PubMed=10576511).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_G364 (KH88)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=8289484
Furukawa T., Koike T., Ying W., Kishi K., Aoki S., Gotoh T., Hashimoto S., Saitoh H., Hanano M., Shinada S., Moriyama Y., Takahashi M., Endo Y., Okano H., Maekawa T., Abe T., Shibata A.
Establishment of a new cell line with the characteristics of a multipotential progenitor from a patient with chronic myelogenous leukemia in early erythroblastic crisis.
Leukemia 8:171-180(1994)

PubMed=9644295; DOI=10.1159/000040837
Kaneko H., Horiike S., Sasai Y., Iwai T., Nakao M., Yokota S., Taniwaki M., Kashima K., Misawa S.-i.
Rare alteration of genomic structure or expression of the DPC4 gene in myelogenous leukemias.
Acta Haematol. 99:187-190(1998)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9
Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.
Leuk. Res. 23:1055-1060(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54899865
Polymorphism and mutation databases Cosmic; 949098
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number13