ID   SBC-2 [Human SCLC]
AC   CVCL_W531
DR   CLO; CLO_0008951
DR   cancercelllines; CVCL_W531
DR   Cell_Model_Passport; SIDM00366
DR   GEO; GSM17312
DR   GEO; GSM827568
DR   JCRB; JCRB0817
DR   LINCS_LDP; LCL-1866
DR   Progenetix; CVCL_W531
DR   Wikidata; Q54952165
RX   CelloPub=CLPUB00132;
RX   DOI=10.4044/joma1947.104.9-10_905;
RX   PubMed=8286010;
RX   PubMed=9290701;
RX   PubMed=9413215;
RX   PubMed=10358721;
RX   PubMed=10628341;
RX   PubMed=15016488;
RX   PubMed=20215515;
RX   PubMed=22399608;
CC   Problematic cell line: Possibly misidentified/contaminated. Shown to be identical to SBC-1 (JCRB web site and STR profile).
CC   Population: Japanese.
CC   Doubling time: 33.8 hours (PubMed=8286010).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
ST   Source(s): JCRB=JCRB0817
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 12
ST   D16S539: 9
ST   D5S818: 9,11
ST   D7S820: 11,12
ST   TH01: 8,9
ST   TPOX: 8
ST   vWA: 14,17
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_1676 ! SBC-1
SX   Male
AG   46Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 10-04-25; Version: 23
//
RX   PubMed=8286010;
RA   Kiura, Katsuyuki
RA   Watarai, Shinobu
RA   Shibayama, Takuo
RA   Ohnoshi, Taisuke
RA   Kimura, Ikuro
RA   Yasuda, Tatsuji
RT   "Inhibitory effects of cholera toxin on in vitro growth of human lung
RT   cancer cell lines.";
RL   Anticancer Drug Des. 8:417-428(1993).
//
RX   PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D;
RA   Jia, Li-Qun
RA   Osada, Motonobu
RA   Ishioka, Chikashi
RA   Gamo, Makio
RA   Ikawa, Shuntaro
RA   Suzuki, Takao
RA   Shimodaira, Hideki
RA   Niitani, Tomohito
RA   Kudo, Toshio
RA   Akiyama, Mitoshi
RA   Kimura, Narimiti
RA   Matsuo, Mitsuyoshi
RA   Mizusawa, Hiroshi
RA   Tanaka, Noriho
RA   Koyama, Hideki
RA   Namba, Masayoshi
RA   Kanamaru, Ryunosuke
RA   Kuroki, Toshio
RT   "Screening the p53 status of human cell lines using a yeast functional
RT   assay.";
RL   Mol. Carcinog. 19:243-253(1997).
//
RX   PubMed=10628341;
RA   Ikubo, Shigeki
RA   Takigawa, Nagio
RA   Ueoka, Hiroshi
RA   Kiura, Katsuyuki
RA   Tabata, Masahiro
RA   Shibayama, Takuo
RA   Chikamori, Masakazu
RA   Aoe, Keisuke
RA   Matsushita, Akio
RA   Harada, Mine
RT   "In vitro evaluation of antimicrotubule agents in human small-cell
RT   lung cancer cell lines.";
RL   Anticancer Res. 19:3985-3988(1999).
//
RX   CelloPub=CLPUB00132;
RA   Kishimoto, Nobuyasu
RA   Ohnoshi, Taisuke
RA   Hiraki, Shunkichi
RA   Miyake, Kenishi
RA   Ozawa, Shiro
RA   Tamura, Tetsuo
RA   Numata, Takeyuki
RA   Kawahara, Shin
RA   Tamura, Ryo
RA   Miyamoto, Hiroaki
RA   Nishii, Kenji
RA   Kimura, Ikuro
RT   "Establishment and characterization of five cell lines from human
RT   small cell carcinoma of the lung.";
RL   Nihon Haigan Gakkai 24:644-644(1984).
//
RX   PubMed=22399608;
RA   Tsuchida, Tadashi
RA   Yamane, Hiromishi
RA   Ochi, Nobuaki
RA   Tabayashi, Takayuki
RA   Hiraki, Akio
RA   Nogami, Naoyuki
RA   Takigawa, Nagio
RA   Kiura, Katsuyuki
RA   Tanimoto, Mitsune
RT   "Cytotoxicity of activated natural killer cells and expression of
RT   adhesion molecules in small-cell lung cancer.";
RL   Anticancer Res. 32:887-892(2012).
//
RX   PubMed=10358721; DOI=10.18926/AMO/31626;
RA   Matsushita, Akio
RA   Tabata, Masahiro
RA   Ueoka, Hiroshi
RA   Kiura, Katsuyuki
RA   Shibayama, Takuo
RA   Aoe, Keisuke
RA   Kohara, Hiroyuki
RA   Harada, Mine
RT   "Establishment of a drug sensitivity panel using human lung cancer
RT   cell lines.";
RL   Acta Med. Okayama 53:67-75(1999).
//
RX   PubMed=15016488; DOI=10.1016/S0140-6736(04)15693-6;
RA   Jones, Michael H.
RA   Virtanen, Carl
RA   Honjoh, Daisuke
RA   Miyoshi, Tatsu
RA   Satoh, Yukitoshi
RA   Okumura, Sakae
RA   Nakagawa, Ken
RA   Nomura, Hitoshi
RA   Ishikawa, Yuichi
RT   "Two prognostically significant subtypes of high-grade lung
RT   neuroendocrine tumours independent of small-cell and large-cell
RT   neuroendocrine carcinomas identified by gene expression profiles.";
RL   Lancet 363:775-781(2004).
//
RX   DOI=10.4044/joma1947.104.9-10_905;
RA   Kishimoto, Nobuyasu
RT   "Studies on cell biology and chemotherapy of lung cancer using tissue
RT   culture techniques. Part 2. Biological characteristics of five newly
RT   established small cell lung cancer cell lines.";
RL   Okayama Igakkai Zasshi 104:905-913(1992).
//
RX   PubMed=9413215;
RA   Yamane, Hiromishi
RA   Kiura, Katsuyuki
RA   Tabata, Masahiro
RA   Bessho, Akihiro
RA   Tsuchida, Tadashi
RA   Motoda, Kinya
RA   Hiraki, Akio
RA   Ueoka, Hiroshi
RA   Harada, Mine
RT   "Small cell lung cancer can express CD34 antigen.";
RL   Anticancer Res. 17:3627-3632(1997).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//