ID   RMS
AC   CVCL_W527
DR   cancercelllines; CVCL_W527
DR   Cosmic; 687961
DR   Cosmic; 801754
DR   Cosmic; 1037299
DR   Cosmic; 1048112
DR   GEO; GSM219593
DR   GEO; GSM1012753
DR   IARC_TP53; 768
DR   PRIDE; PXD039480
DR   Progenetix; CVCL_W527
DR   Wikidata; Q54950688
RX   PubMed=2216456;
RX   PubMed=2486618;
RX   PubMed=18082704;
RX   PubMed=19235922;
RX   PubMed=23578105;
RX   PubMed=23665679;
RX   PubMed=36768928;
CC   Population: Japanese.
CC   Doubling time: 20-24 hours (PubMed=2486618).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Unspecified (PubMed=2216456).
CC   Omics: SNP array analysis.
CC   Omics: Cell surface proteome.
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   4Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 19-12-24; Version: 17
//
RX   PubMed=2216456;
RA   Stratton M.R., Moss S., Warren W., Patterson H., Clark J., Fisher C.,
RA   Fletcher C.D.M., Ball A.B.S., Thomas M., Gusterson B.A., Cooper C.S.;
RT   "Mutation of the p53 gene in human soft tissue sarcomas: association
RT   with abnormalities of the RB1 gene.";
RL   Oncogene 5:1297-1301(1990).
//
RX   PubMed=2486618;
RA   Kato K., Ikeda H., Akiyama Y., Suda J., Eguchi M., Furukawa T.;
RT   "Establishment and characterization of human rhabdomyosarcoma cell
RT   line (RMS).";
RL   Hum. Cell 2:214-215(1989).
//
RX   PubMed=18082704; DOI=10.1016/j.jpedsurg.2007.08.026;
RA   Komuro H., Saihara R., Shinya M., Takita J., Kaneko S., Kaneko M.,
RA   Hayashi Y.;
RT   "Identification of side population cells (stem-like cell population)
RT   in pediatric solid tumor cell lines.";
RL   J. Pediatr. Surg. 42:2040-2045(2007).
//
RX   PubMed=19235922; DOI=10.1002/gcc.20655;
RA   Missiaglia E., Selfe J., Hamdi M., Williamson D., Schaaf G., Fang C.,
RA   Koster J., Summersgill B.M., Messahel B., Versteeg R.,
RA   Pritchard-Jones K., Kool M., Shipley J.M.;
RT   "Genomic imbalances in rhabdomyosarcoma cell lines affect expression
RT   of genes frequently altered in primary tumors: an approach to identify
RT   candidate genes involved in tumor development.";
RL   Genes Chromosomes Cancer 48:455-467(2009).
//
RX   PubMed=23578105; DOI=10.1111/cas.12173; PMCID=PMC7657110;
RA   Nishimura R., Takita J., Sato-Otsubo A., Kato M., Koh K., Hanada R.,
RA   Tanaka Y., Kato K., Maeda D., Fukayama M., Sanada M., Hayashi Y.,
RA   Ogawa S.;
RT   "Characterization of genetic lesions in rhabdomyosarcoma using a
RT   high-density single nucleotide polymorphism array.";
RL   Cancer Sci. 104:856-864(2013).
//
RX   PubMed=23665679; DOI=10.1038/onc.2013.129;
RA   Sokolowski E., Turina C.B., Kikuchi K., Langenau D.M., Keller C.;
RT   "Proof-of-concept rare cancers in drug development: the case for
RT   rhabdomyosarcoma.";
RL   Oncogene 33:1877-1889(2014).
//
RX   PubMed=36768928; DOI=10.3390/ijms24032601; PMCID=PMC9917031;
RA   Timpanaro A., Piccand C., Uldry A.-C., Bode P.-K., Dzhumashev D.,
RA   Sala R., Heller M., Rossler J., Bernasconi M.;
RT   "Surfaceome profiling of cell lines and patient-derived xenografts
RT   confirm FGFR4, NCAM1, CD276, and highlight AGRL2, JAM3, and L1CAM as
RT   surface targets for rhabdomyosarcoma.";
RL   Int. J. Mol. Sci. 24:2601.1-2601.28(2023).
//