Cell line name |
LMF4 |
Accession |
CVCL_W515 |
Resource Identification Initiative |
To cite this cell line use: LMF4 (RRID:CVCL_W515) |
Comments |
Population: Japanese. Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429. |
Sequence variations |
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Glu120Ter (c.358G>T); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys305fs (c.912_913insTAAG); Zygosity=Unspecified (from parent cell line).
|
Disease |
Tongue squamous cell carcinoma (NCIt: C4648) Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_1288 (HSC-3) |
Sex of cell |
Male |
Age at sampling |
64Y |
Category |
Cancer cell line |
Publications | PubMed=2585303; DOI=10.1111/j.1600-0714.1989.tb01570.x Momose F., Araida T., Negishi A., Ichijo H., Shioda S., Sasaki S. Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas. J. Oral Pathol. Med. 18:391-395(1989) PubMed=11755821; DOI=10.1016/S1368-8375(01)00022-7 Niinaka Y., Haga A., Negishi A., Yoshimasu H., Raz A., Amagasa T. Regulation of cell motility via high and low affinity autocrine motility factor (AMF) receptor in human oral squamous carcinoma cells. Oral Oncol. 38:49-55(2002) PubMed=16127291; DOI=10.1159/000087910 Bhawal U.K., Ozaki Y., Nishimura M., Sugiyama M., Sasahira T., Nomura Y., Sato F., Fujimoto K., Sasaki N., Ikeda M.-a., Tsuji K., Kuniyasu H., Kato Y. Association of expression of receptor for advanced glycation end products and invasive activity of oral squamous cell carcinoma. Oncology 69:246-255(2005) |
Cross-references |
Encyclopedic resources |
Wikidata; Q54902756
|
Entry history |
Entry creation | 16-Apr-2014 |
Last entry update | 19-Dec-2024 |
Version number | 13 |
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