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Cellosaurus LMF4 (CVCL_W515)

[Text version]
Cell line name LMF4
Accession CVCL_W515
Resource Identification Initiative To cite this cell line use: LMF4 (RRID:CVCL_W515)
Comments Population: Japanese.
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Glu120Ter (c.358G>T); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys305fs (c.912_913insTAAG); Zygosity=Unspecified (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1288 (HSC-3)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=2585303; DOI=10.1111/j.1600-0714.1989.tb01570.x
Momose F., Araida T., Negishi A., Ichijo H., Shioda S., Sasaki S.
Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas.
J. Oral Pathol. Med. 18:391-395(1989)

PubMed=11755821; DOI=10.1016/S1368-8375(01)00022-7
Niinaka Y., Haga A., Negishi A., Yoshimasu H., Raz A., Amagasa T.
Regulation of cell motility via high and low affinity autocrine motility factor (AMF) receptor in human oral squamous carcinoma cells.
Oral Oncol. 38:49-55(2002)

PubMed=16127291; DOI=10.1159/000087910
Bhawal U.K., Ozaki Y., Nishimura M., Sugiyama M., Sasahira T., Nomura Y., Sato F., Fujimoto K., Sasaki N., Ikeda M.-a., Tsuji K., Kuniyasu H., Kato Y.
Association of expression of receptor for advanced glycation end products and invasive activity of oral squamous cell carcinoma.
Oncology 69:246-255(2005)

Cross-references
Encyclopedic resources Wikidata; Q54902756
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number13