Cell line name |
EIIL |
Accession |
CVCL_W441 |
Resource Identification Initiative |
To cite this cell line use: EIIL (RRID:CVCL_W441) |
Comments |
Population: Japanese. Characteristics: Estrogen-independent (PubMed=7699285). Derived from site: In situ; Endometrium; UBERON=UBERON_0001295. |
Sequence variations |
- Mutation; HGNC; 8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
|
Disease |
Endometrial adenocarcinoma (NCIt: C7359) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_2529 (Ishikawa) |
Sex of cell |
Female |
Age at sampling |
39Y |
Category |
Cancer cell line |
Publications | PubMed=7699285 Sakamoto H., Deng X.-H., Shirakawa T., Ige S., Ohtani K., Saitoh A., Takami M., Takami T., Satoh K. Establishment of metastatic sub-clone from estrogen independent Ishikawa cells and its characterization in vitro and in vivo. Nihon Sanka Fujinka Gakkai Zasshi 47:249-256(1995) PubMed=8718550 Shirakawa T., Sakamoto H., Satoh K. Separation and characterization of estrogen independent endometrial cancer cell line originated from Ishikawa strain. Nihon Sanka Fujinka Gakkai Zasshi 48:139-146(1996) PubMed=10381137; DOI=10.1016/S0304-3835(98)00270-5 Ohta H., Sakamoto H., Satoh K. In vitro effects of gonadotropin-releasing hormone (GnRH) analogue on cancer cell sensitivity to cis-platinum. Cancer Lett. 134:111-118(1998) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_W441
|
Encyclopedic resources |
Wikidata; Q54832166
|
Entry history |
Entry creation | 16-Apr-2014 |
Last entry update | 05-Oct-2023 |
Version number | 10 |
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