| Cell line name |
Ishikawa 2-B-12 |
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| Accession |
CVCL_W427 |
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| Resource Identification Initiative |
To cite this cell line use: Ishikawa 2-B-12 (RRID:CVCL_W427) |
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| Comments |
Population: Japanese.
Doubling time: 36.5 hours (PubMed=9183638).
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295. |
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| Sequence variations |
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Type I endometrial adenocarcinoma (NCIt: C40145) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_2529 (Ishikawa) |
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| Sex of cell |
Female |
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| Age at sampling |
39Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=9183638
Nishida M., Kasahara K., Oki A., Satoh T., Arai Y., Kubo T.
Establishment of eighteen clones of Ishikawa cells.
Hum. Cell 9:109-116(1996) DOI=10.1007/978-4-431-53981-0_2
Nishida M.
Ishikawa cells: opening of in vitro hormone research on endometrial carcinoma.
(In book chapter) Cell and molecular biology of endometrial carcinoma; Kuramoto H., Nishida M. (eds.); pp.35-58; Springer; Tokyo; Japan (2003) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_W427
|
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| Encyclopedic resources |
Wikidata; Q54898290
|
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| Entry history |
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| Entry creation | 16-Apr-2014 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 11 |
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